World Gastroenterology Organisation Global Guideline Helicobacter pylori in Developing Countries
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National Institute for Health and Clinical Excellence (NICE), UK (2004) http://guidance.nice.org.uk/ CG17 Scottish Intercollegiate Guidelines Network (SIGN), UK (2003) http://www.sign.ac.uk/pdf/ 2009dyspepsiareport.pdf J Clin Gastroenterol Volume 45, Number 5, May/June 2011 WGO Article r 2011 Lippincott Williams & Wilkins www.jcge.com | 387 Note 8. In Brazil, patients with a history of allergy to penicillin receive PPI+clarithromycin (500mg) and furazolidone (200mg) twice daily for 7 days. Note 9. Reports from Asia suggest that 1 week of triple PPI therapy with clarithromycin and amoxicillin is still a useful form of treatment. Metronidazole resistance in Asia is close to 80% (in vitro). Note 10. Prescribers should be aware of drug resistance patterns in their own area (particularly with regard to clarithromycin) before deciding on a particular regimen. Gold Standard Treatment Options Further information on gold standard treatment options is available in the documents listed in Table 9. Treatment Options in Developing Countries (Table 10) Lower-cost Options for Limited-resource Settings (Table 11) TABLE 10. Treatment Options in Developing Countries
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World Gastroenterology Organisation Global Guideline: Helicobacter pylori in developing countries.
In developing countries, H. pylori infection is a public health issue. The high prevalence of the infection means that public health interventions may be required. Therapeutic vaccination is probably the only strategy that would make a decisive difference in the prevalence and incidence of H. pylori throughout the world. The short-term approach, however – provided that resources allow for this ...
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